TY - JOUR
T1 - Clinical features of individuals with schizotypal personality disorder with and without suicidal ideation
AU - Sher, Leo
AU - Challman, Katelyn N.
AU - Smith, Emma C.
AU - New, Antonia S.
AU - Perez-Rodriguez, M. Mercedes
AU - McClure, Margaret M.
AU - Goodman, Marianne
AU - Kahn, René S.
AU - Hazlett, Erin A.
N1 - Publisher Copyright:
© 2023
PY - 2023/4
Y1 - 2023/4
N2 - This study compared demographic and clinical features in a sample of 384 participants: healthy controls (HC; n = 166) and individuals with schizotypal personality disorder (SPD) with (n = 50) and without (n = 168) suicidal ideation (SI) to examine specific risk factors for suicidality in SPD. Compared to the non-SI group, the SI group showed significantly greater severity of depression, aggression, impulsivity, affective lability, schizotypal features, poorer social adjustment, and had fewer social contacts. Individuals in the SI group were also more likely to have a history of a suicide attempt and comorbid borderline personality disorder in comparison to the non-SI group. Logistic regression analysis indicated that severity of depression and the number of social contacts drove the difference between the SI and non-SI groups. Compared with both SPD subgroups, the HC group was significantly less depressed, aggressive, impulsive, affectively labile, had fewer schizotypal features, was better socially adjusted, and had more social contacts. This study indicates that overall, the SI group is a more severely impaired group of individuals with SPD compared to the non-SI group. Better educating medical professionals about the diagnosis and management of SPD and its associations with suicidality is warranted.
AB - This study compared demographic and clinical features in a sample of 384 participants: healthy controls (HC; n = 166) and individuals with schizotypal personality disorder (SPD) with (n = 50) and without (n = 168) suicidal ideation (SI) to examine specific risk factors for suicidality in SPD. Compared to the non-SI group, the SI group showed significantly greater severity of depression, aggression, impulsivity, affective lability, schizotypal features, poorer social adjustment, and had fewer social contacts. Individuals in the SI group were also more likely to have a history of a suicide attempt and comorbid borderline personality disorder in comparison to the non-SI group. Logistic regression analysis indicated that severity of depression and the number of social contacts drove the difference between the SI and non-SI groups. Compared with both SPD subgroups, the HC group was significantly less depressed, aggressive, impulsive, affectively labile, had fewer schizotypal features, was better socially adjusted, and had more social contacts. This study indicates that overall, the SI group is a more severely impaired group of individuals with SPD compared to the non-SI group. Better educating medical professionals about the diagnosis and management of SPD and its associations with suicidality is warranted.
KW - Depression
KW - Schizotypal personality disorder
KW - Social adjustment
KW - Suicidal ideation
UR - http://www.scopus.com/inward/record.url?scp=85148671554&partnerID=8YFLogxK
U2 - 10.1016/j.psychres.2023.115132
DO - 10.1016/j.psychres.2023.115132
M3 - Article
AN - SCOPUS:85148671554
SN - 0165-1781
VL - 322
JO - Psychiatry Research
JF - Psychiatry Research
M1 - 115132
ER -