Clinical expression of LRRK2 G2019S mutations in the elderly

Keyphrases

• Clinical Expression 100%
• G2019S mutation 100%
• Leucine-rich Repeat Kinase 2 (LRRK2) 100%
• Unified Parkinson's Disease Rating Scale (UPDRS) 100%
• Parkinson's Disease 66%
• Aging Studies 66%
• Control Subjects 33%
• Jewish Population 33%
• Ashkenazi Jews 33%
• Small Sample Size 33%
• Largest Subset 33%
• Natural History 33%
• Age-dependent 33%
• Non-carriers 33%
• Mutation Carriers 33%
• Reduced Penetrance 33%
• Autosomal Dominant 33%
• Longitudinal Data 33%
• Community-based 33%
• Penetrance 33%
• Etiology of Parkinson's Disease 33%
• Cognitive Examination 33%
• Motor Assessment 33%
• Albert Einstein 33%
• PARK8 33%
• Motor Score 33%
• Motor Decline 33%
• Monogenic Etiology 33%
• Phenoconversion 33%

Biochemistry, Genetics and Molecular Biology

• Penetrance 100%
• LRRK2 100%
• Kinase 50%
• Phosphotransferase 50%
• Leucine-Rich Repeat 50%
• Cohort Study 50%
• Sample Size 50%
• Autosomal Dominant Inheritance 50%

Neuroscience

• Parkinson's Disease 100%
• Leucine Rich Repeat Kinase 2 33%
• Etiology of Parkinson's Disease 33%