TY - JOUR
T1 - Clinical Experience with a Porcine Aortic Valve Xenograft for Mitral Valve Replacement
AU - Stinson, Edward B.
AU - Griepp, Randall B.
AU - Shumway, Norman E.
PY - 1974
Y1 - 1974
N2 - Between March, 1971, and July, 1973, 103 patients underwent mitral valve replacement with a glutaraldehyde-preserved porcine aortic valve mounted on a flexible polypropylene, Dacron-covered stent. Overall operative survival was 95.1%. Actuarial analysis of late postoperative results indicates 92% survival through 2 years, with functional improvement in nearly all patients. The rate of systemic thromboembolism has been approximately 1.7% per patient-year without anticoagulants. No valve failure has occurred. We conclude that this xenograft prosthesis provides a technically and functionally satisfactory valve substitute, the durability of which appears to significantly exceed that of previously available tissue valves for mitral replacement.
AB - Between March, 1971, and July, 1973, 103 patients underwent mitral valve replacement with a glutaraldehyde-preserved porcine aortic valve mounted on a flexible polypropylene, Dacron-covered stent. Overall operative survival was 95.1%. Actuarial analysis of late postoperative results indicates 92% survival through 2 years, with functional improvement in nearly all patients. The rate of systemic thromboembolism has been approximately 1.7% per patient-year without anticoagulants. No valve failure has occurred. We conclude that this xenograft prosthesis provides a technically and functionally satisfactory valve substitute, the durability of which appears to significantly exceed that of previously available tissue valves for mitral replacement.
UR - http://www.scopus.com/inward/record.url?scp=0016215785&partnerID=8YFLogxK
U2 - 10.1016/S0003-4975(10)64376-7
DO - 10.1016/S0003-4975(10)64376-7
M3 - Article
C2 - 4278733
AN - SCOPUS:0016215785
SN - 0003-4975
VL - 18
SP - 391
EP - 401
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 4
ER -