Clinical and experimental basis of high frequency jet ventilation

HFJV defines a form of mechanical ventilation which delivers tidal volumes of 3-6 ml/kg 100-300 times/minute. Mean airway pressure is not different from that observed with conventional ventilation; however, peak inspiratory pressure is considerably lower. The goal of respiratory support with HFJV is not to maximize lung volume and minimize shunt fraction but to favor diffusion over convection at relatively stable lung volume. HFJV is probably the best form of ventilation for patients with major airway disruption.