Abstract
A 35-year-old male presented with chronic myelomonocytic leukemia (CMMoL) after 6.5 years of alkylating agent therapy for IgG-κ type multiple myeloma. The total dose of melphalan was 0.648 g. CMMoL was stable with weekly injection of α-interferon for one year. Thereafter, monocytosis and thrombocytopenia aggravated, and the patient died of disseminating intravascular coagulation. Prolonged drug therapy can induce CMMoL, as well as other myelodysplastic syndromes.
Original language | English |
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Pages (from-to) | 263-265 |
Number of pages | 3 |
Journal | International Journal of Hematology |
Volume | 60 |
Issue number | 4 |
DOIs | |
State | Published - Dec 1994 |
Externally published | Yes |