TY - JOUR
T1 - Chronic Lyme arthritis and HLA alleles (Reply)
AU - Steere, A. C.
AU - Winchester, R.
AU - Dwyer, E.
PY - 1991
Y1 - 1991
N2 - To the Editor: In their paper in the July 26 issue,1 Steere et al. state in the Results section that the frequency of HLA-DR4 was significantly greater in patients with chronic arthritis than in normal subjects (57 vs. 31 percent, P<0.01). This statement is evidently incorrect; in fact, the correct P value (calculated by Fisher's exact test and then multiplied by the number of specificities tested at each locus, as stated in the Methods section) is 0.014 × 7, or 0.1, as reported in Table 1 in the paper. Thus, HLA-DR4 seems to be more frequent in patients with chronic. .
AB - To the Editor: In their paper in the July 26 issue,1 Steere et al. state in the Results section that the frequency of HLA-DR4 was significantly greater in patients with chronic arthritis than in normal subjects (57 vs. 31 percent, P<0.01). This statement is evidently incorrect; in fact, the correct P value (calculated by Fisher's exact test and then multiplied by the number of specificities tested at each locus, as stated in the Methods section) is 0.014 × 7, or 0.1, as reported in Table 1 in the paper. Thus, HLA-DR4 seems to be more frequent in patients with chronic. .
UR - http://www.scopus.com/inward/record.url?scp=0025977546&partnerID=8YFLogxK
U2 - 10.1056/NEJM199101103240215
DO - 10.1056/NEJM199101103240215
M3 - Letter
C2 - 1984182
AN - SCOPUS:0025977546
SN - 0028-4793
VL - 324
SP - 129
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 2
ER -