TY - JOUR
T1 - Chronic lung disease secondary to ammonia inhalation injury
T2 - A report on three cases
AU - De La Hoz, Rafael E.
AU - Schlueter, Donald P.
AU - Rom, William N.
PY - 1996/2
Y1 - 1996/2
N2 - Inhalation of highly hydrosoluble toxicants, like ammonia, can be associated with chronic lung diseases, which have been partially characterized. We present the cases of three patients who were evaluated 2 years after massive exposure to ammonia in occupational settings. They presented with chronic dyspnea, and clinical pictures consistent with restrictive lung dysfunction, obstructive lung disease, and bronchial hyper- reactivity and small airways disease, respectively. The findings in 94 reported cases of inhalation injury due to massive exposure to ammonia are reviewed; in 35 cases follow-up for at least 1 year was available. The range of chronic pulmonary diseases associated with ammonia inhalation injury is reviewed, and suggestions for appropriate diagnostic evaluation are made.
AB - Inhalation of highly hydrosoluble toxicants, like ammonia, can be associated with chronic lung diseases, which have been partially characterized. We present the cases of three patients who were evaluated 2 years after massive exposure to ammonia in occupational settings. They presented with chronic dyspnea, and clinical pictures consistent with restrictive lung dysfunction, obstructive lung disease, and bronchial hyper- reactivity and small airways disease, respectively. The findings in 94 reported cases of inhalation injury due to massive exposure to ammonia are reviewed; in 35 cases follow-up for at least 1 year was available. The range of chronic pulmonary diseases associated with ammonia inhalation injury is reviewed, and suggestions for appropriate diagnostic evaluation are made.
KW - ammonia
KW - asthma
KW - lung diseases
KW - occupational diseases
UR - http://www.scopus.com/inward/record.url?scp=0030044667&partnerID=8YFLogxK
U2 - 10.1002/(SICI)1097-0274(199602)29:2<209::AID-AJIM12>3.0.CO;2-7
DO - 10.1002/(SICI)1097-0274(199602)29:2<209::AID-AJIM12>3.0.CO;2-7
M3 - Article
C2 - 8821365
AN - SCOPUS:0030044667
SN - 0271-3586
VL - 29
SP - 209
EP - 214
JO - American Journal of Industrial Medicine
JF - American Journal of Industrial Medicine
IS - 2
ER -