Abstract
Chronic hepatitis B and C infection are the leading causes of hepatocellular carcinoma and liver related death in the world and in the United States respectively. Screening guidelines have been developed based on estimated prevalence determined by NHANES data. However, individuals with the most risk of chronic infection (incarcerated, homeless, immigrants, nursing home residents, and hospitalized persons) are underrepresented in this cohort leading to an underestimation of the true prevalence of chronic hepatitis B and C infection. This has led to recent updates in the screening guidelines. This review examines the change in the guidelines, the likely true seroprevalence of hepatitis B and C virus, as well as the burden of chronic infection in this population.
| Original language | English |
|---|---|
| Pages (from-to) | 511-521 |
| Number of pages | 11 |
| Journal | Expert Review of Anti-Infective Therapy |
| Volume | 14 |
| Issue number | 5 |
| DOIs | |
| State | Published - 3 May 2016 |
Keywords
- Chronic hepatitis B
- chronic hepatitis C
- guidelines
- prevalence
- screening
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