Chronic granulomatous disease of childhood presenting as gastric outlet obstruction

V. A. Varma, J. T. Sessions, L. B. Kahn, S. Lipper

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

A case of chronic granulomatous disease of childhood was first diagnosed when a 20-month-old infant developed gastric outlet obstruction. Because of the unusual clinical presentation and negative gastric mucosal biopsies, the diagnosis was delayed. A subsequent full thickness biopsy of the stomach wall which led to a correct diagnosis showed a granulomatous infiltrate in the muscularis propria. Characteristic yellow pigment-laden macrophages were seen in the gastric mucosa and pyloric lymph node. Early recognition of this chronic disorder is important not only for proper management but genetic counselling as well.

Original languageEnglish
Pages (from-to)673-676
Number of pages4
JournalAmerican Journal of Surgical Pathology
Volume6
Issue number7
DOIs
StatePublished - 1982
Externally publishedYes

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