This review is confined principally to only some of the major recent findings, primarily those published in the last 2 years. It has 79 references and concludes that the new banding techniques are providing a growing body of information which relates specific chromosome aberrations to various forms of leukemia and cancer. Studies of the localization of chromosome damage induced by known possible oncogenic agents may allow correlation between such agents and the specific tumors they may cause. Additional new techniques, such as the detection of sister chromatid exchange and the accurate mapping and immunologic study of viruses associated with neoplasia, may help in understanding the mechanisms involved in the relation between chromosomes and cancer.
|Number of pages||9|
|Journal||Birth Defects: Original Article Series|
|State||Published - 1976|