Chromosome #14 markers in two Epstein-Barr Virus (EBV)-transformed lymphoblastoid cell lines of normal origin differ from the Burkitt lymphoma (BL)-associated 14q+ marker

George Manolov, Yanka Manolova, George Klein, Albert Levan, Jörgen Kieler

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5 Scopus citations

Abstract

Two among ten Epstein-Barr Virus (EBV)-transformed lymphoblastoid cell lines contained a 14q+ marker in a low frequency of the cells (2 and 9%). By means of "mesome-prosome" analysis of the G-band patterns of these markers; it was established that the additional chromosome segments of these two 14q+ markers came from chromosomes #3 and #5, respectively, and not from chromosome #8 as in the 14q+ marker of Burkitt lymphoma. Chromosome #8 was not involved at all in any changes in the ten lymphoblastoid cell lines studied.

Original languageEnglish
Pages (from-to)179-184
Number of pages6
JournalCancer Genetics and Cytogenetics
Volume4
Issue number2
DOIs
StatePublished - Oct 1981
Externally publishedYes

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