Chromatic and luminance systems deficits in glaucoma

Vivienne C. Greenstein, Daniel Halevy, Qasim Zaidi, Karen L. Koenig, Robert H. Ritch

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

The purpose of this study was to compare the effects of glaucoma, at different stages of the disease process, on the two color-opponent systems and on the luminance system. Discrimination thresholds were measured along the two equiluminant cardinal color axes (RG and YV) and along an achromatic luminance axis (LD) in 27 patients with open-angle glaucoma (GAG) and in 13 glaucoma suspects. Patients with OAG showed increased thresholds along all three axes. The threshold increases correlated significantly with the level of visual field loss. For glaucoma suspects, thresholds were also increased along all three axes. A subgroup of patients with GAG, those with pigmentary glaucoma, showed minimal increases in threshold along the RG axis. To further investigate this finding an additional 15 patients, seven with primary OAG and eight with pigmentary glaucoma were run in a two-alternative forced-choice experiment. For patients with pigmentary glaucoma, thresholds were increased less along the RG axis. The results of the study for OAG patients and glaucoma suspects are consistent with deficits in the two color-opponent systems, and in the luminance system.

Original languageEnglish
Pages (from-to)621-629
Number of pages9
JournalVision Research
Volume36
Issue number4
DOIs
StatePublished - Feb 1996
Externally publishedYes

Keywords

  • Colour opponent systems
  • Discrimination thresholds
  • Glaucoma
  • Psychophysics

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