Cholinergic dysautonomia and eaton-lambert syndrome

Allan E. Rubenstein, Steven H. Horowitz, Adam N. Bender

Research output: Contribution to journalArticlepeer-review

45 Scopus citations


Cholinergic autonomic function was abnormal in a 47-year-old woman with Eaton-Lambert syndrome (ELS), not associated with carcinoma. Pupillary constriction to light and accommodation, sweating, lacrimation, and salivation were all affected. There was no evidence of Sjogren syndrome or botulinum intoxication. The defect of acetylcholine release from presynaptic terminals in the Eaton-Lambert syndrome may not be restricted to the neuromuscular junction of skeletal muscle.

Original languageEnglish
Pages (from-to)720-723
Number of pages4
Issue number5
StatePublished - May 1979
Externally publishedYes


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