Choline chloride treatment of memory deficits in the elderly

R. C. Mohs; K. L. Davis; J. R. Tinklenberg; L. E. Hollister; J. A. Yesavage; B. S. Kopell

doi:10.1176/ajp.136.10.1275

Choline chloride treatment of memory deficits in the elderly

R. C. Mohs, K. L. Davis, J. R. Tinklenberg, L. E. Hollister, J. A. Yesavage, B. S. Kopell

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Abstract

Eight elderly patients with mild memory impairment were given choline chloride, a drug that increases brain acetylcholine concentrations. After 16 g/day of choline for 7 days, average memory performance was not different from performances during pre- and postcholine placebo treatment, although the patient with the poorest baseline performance improved considerably on choline.

Original language	English
Pages (from-to)	1275-1277
Number of pages	3
Journal	American Journal of Psychiatry
Volume	136
Issue number	10
DOIs	https://doi.org/10.1176/ajp.136.10.1275
State	Published - 1979
Externally published	Yes

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title = "Choline chloride treatment of memory deficits in the elderly",

abstract = "Eight elderly patients with mild memory impairment were given choline chloride, a drug that increases brain acetylcholine concentrations. After 16 g/day of choline for 7 days, average memory performance was not different from performances during pre- and postcholine placebo treatment, although the patient with the poorest baseline performance improved considerably on choline.",

author = "Mohs, {R. C.} and Davis, {K. L.} and Tinklenberg, {J. R.} and Hollister, {L. E.} and Yesavage, {J. A.} and Kopell, {B. S.}",

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AU - Davis, K. L.

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AU - Hollister, L. E.

AU - Yesavage, J. A.

AU - Kopell, B. S.

PY - 1979

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AB - Eight elderly patients with mild memory impairment were given choline chloride, a drug that increases brain acetylcholine concentrations. After 16 g/day of choline for 7 days, average memory performance was not different from performances during pre- and postcholine placebo treatment, although the patient with the poorest baseline performance improved considerably on choline.

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EP - 1277

JO - American Journal of Psychiatry

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Choline chloride treatment of memory deficits in the elderly

Abstract

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