Choline chloride in schizophrenia

K. L. Davis, L. E. Hollister, P. A. Berger

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


The authors investigated the possibility that choline chloride might reduce schizophrenic symptoms by increasing central cholinergic activity. In a single blind crossover study, up to 20 g/day of choline chloride had no significant effect on clinical ratings of nine schizophrenic patients. However, there was some evidence that choline significantly increased symptoms of depression.

Original languageEnglish
Pages (from-to)1581-1584
Number of pages4
JournalAmerican Journal of Psychiatry
Issue number12
StatePublished - 1979
Externally publishedYes


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