Cholestatic Jaundice

James K. O'donnell; Robert P. Yatto; Jerome H. Siegel; David S. Zimmon; Arthur R. Clemett; Avram M. Cooperman; Jerome F. Wiot; Robert A. Clark; Bruce F. Scharschmidt

doi:10.1056/NEJM198311103091916

Cholestatic Jaundice

James K. O'donnell, Robert P. Yatto, Jerome H. Siegel, David S. Zimmon, Arthur R. Clemett, Avram M. Cooperman, Jerome F. Wiot, Robert A. Clark, Bruce F. Scharschmidt

Research output: Contribution to journal › Letter › peer-review

Abstract

To the Editor: The review by Scharschmidt et al. of approaches to the patient with cholestatic jaundice (June 23 issue)¹ is inaccurate in its dismissal of cholescintigraphy as a routine procedure in the evaluation of these patients. The papers cited to document the shortcomings of radioisotope techniques² ³ ⁴ use data from studies performed before 1981 with technetium-99m-iminodiacetic acid analogues now considered suboptimal for imaging in patients with elevated serum bilirubin. Most institutions now use technetium-99m disofenin as the radiopharmaceutical of choice, since it has been shown to give diagnostic results despite bilirubin levels approaching 40 mg per 100 ml.⁵^,⁶ In addition,.

Original language	English
Pages (from-to)	1191-1193
Number of pages	3
Journal	New England Journal of Medicine
Volume	309
Issue number	19
DOIs	https://doi.org/10.1056/NEJM198311103091916
State	Published - 10 Nov 1983
Externally published	Yes

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title = "Cholestatic Jaundice",

abstract = "To the Editor: The review by Scharschmidt et al. of approaches to the patient with cholestatic jaundice (June 23 issue)1 is inaccurate in its dismissal of cholescintigraphy as a routine procedure in the evaluation of these patients. The papers cited to document the shortcomings of radioisotope techniques2 3 4 use data from studies performed before 1981 with technetium-99m-iminodiacetic acid analogues now considered suboptimal for imaging in patients with elevated serum bilirubin. Most institutions now use technetium-99m disofenin as the radiopharmaceutical of choice, since it has been shown to give diagnostic results despite bilirubin levels approaching 40 mg per 100 ml.5,6 In addition,.",

author = "O'donnell, {James K.} and Yatto, {Robert P.} and Siegel, {Jerome H.} and Zimmon, {David S.} and Clemett, {Arthur R.} and Cooperman, {Avram M.} and Wiot, {Jerome F.} and Clark, {Robert A.} and Scharschmidt, {Bruce F.}",

year = "1983",

month = nov,

day = "10",

doi = "10.1056/NEJM198311103091916",

language = "English",

volume = "309",

pages = "1191--1193",

journal = "New England Journal of Medicine",

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TY - JOUR

T1 - Cholestatic Jaundice

AU - O'donnell, James K.

AU - Yatto, Robert P.

AU - Siegel, Jerome H.

AU - Zimmon, David S.

AU - Clemett, Arthur R.

AU - Cooperman, Avram M.

AU - Wiot, Jerome F.

AU - Clark, Robert A.

AU - Scharschmidt, Bruce F.

PY - 1983/11/10

Y1 - 1983/11/10

N2 - To the Editor: The review by Scharschmidt et al. of approaches to the patient with cholestatic jaundice (June 23 issue)1 is inaccurate in its dismissal of cholescintigraphy as a routine procedure in the evaluation of these patients. The papers cited to document the shortcomings of radioisotope techniques2 3 4 use data from studies performed before 1981 with technetium-99m-iminodiacetic acid analogues now considered suboptimal for imaging in patients with elevated serum bilirubin. Most institutions now use technetium-99m disofenin as the radiopharmaceutical of choice, since it has been shown to give diagnostic results despite bilirubin levels approaching 40 mg per 100 ml.5,6 In addition,.

AB - To the Editor: The review by Scharschmidt et al. of approaches to the patient with cholestatic jaundice (June 23 issue)1 is inaccurate in its dismissal of cholescintigraphy as a routine procedure in the evaluation of these patients. The papers cited to document the shortcomings of radioisotope techniques2 3 4 use data from studies performed before 1981 with technetium-99m-iminodiacetic acid analogues now considered suboptimal for imaging in patients with elevated serum bilirubin. Most institutions now use technetium-99m disofenin as the radiopharmaceutical of choice, since it has been shown to give diagnostic results despite bilirubin levels approaching 40 mg per 100 ml.5,6 In addition,.

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DO - 10.1056/NEJM198311103091916

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JO - New England Journal of Medicine

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Cholestatic Jaundice

Abstract

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