Chloroquine inhibits intracellular degradation but not secretion of Alzheimer β/A4 amyloid precursor protein

Keyphrases

• Amyloid Precursor Protein 100%
• Alzheimer 100%
• Intracellular Degradation 100%
• Chloroquine 100%
• C-terminal Fragments 40%
• Golgi 30%
• Protein Maturation 30%
• Proteolysis 20%
• Endoplasmic Reticulum 10%
• Cell-Associated 10%
• Inhibitory Effect 10%
• PC12 Cells 10%
• Protein Secretion 10%
• Lysosomotropic Agents 10%
• Resorption 10%
• Amyloidogenic Processing 10%
• Trans-Golgi Network 10%
• Acidic Compartments 10%
• N-glycosylation 10%
• Monensin 10%
• Protein Cleavage 10%
• Protein Processing 10%
• O-glycosylation 10%
• Metabolic Fate 10%
• Brefeldin A 10%
• Protein Recovery 10%
• Endosomal System 10%
• Tyrosine Sulfation 10%

Immunology and Microbiology

• Secretion (Process) 100%
• Precursor 100%
• Chloroquine 100%
• Protein Processing 45%
• Carboxy Terminal Sequence 36%
• Protein Degradation 18%
• Endoplasmic reticulum 9%
• Amino Terminal Sequence 9%
• Glycosylation 9%
• Protein Secretion 9%
• Sulfation 9%
• Protein Cleavage 9%
• PC12 Cell Line 9%
• Trans Golgi Network 9%
• Tyrosine 9%

Biochemistry, Genetics and Molecular Biology

• Secretion (Process) 100%
• Amyloid Precursor Protein 100%
• Posttranslational Modification 45%
• C-Terminus 36%
• Proteolysis 18%
• N-Terminus 9%
• Protein Secretion 9%
• Glycosylation 9%
• Protein Cleavage 9%
• Holoprotein 9%
• Tyrosine Sulfation 9%