Childhood Growth Hormone Deficiency and Hypopituitarism

Carmen L. Soto-Rivera; Christopher J. Romero; Laurie E. Cohen

doi:10.1007/978-3-319-73782-9_1

Childhood Growth Hormone Deficiency and Hypopituitarism

Carmen L. Soto-Rivera
, Christopher J. Romero
, Laurie E. Cohen

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

5 Scopus citations

Abstract

Hypopituitarism is the deficiency in varying degrees of one or multiple pituitary hormones. In this chapter, deficiency of growth hormone (GH) will be discussed, while other hormonal deficiencies are presented elsewhere in this book. To understand GH deficiency (GHD), the mechanisms of GH production and its secretion are first presented. There are multiple etiologies of GHD, and an ever-increasing number of genetic causes have been uncovered. However, the ability to make the diagnosis of GHD still remains difficult, and interpretation of laboratory studies remains controversial.

Original language	English
Title of host publication	Pediatric Endocrinology
Subtitle of host publication	A Practical Clinical Guide
Publisher	Springer Science+Business Media
Pages	3-29
Number of pages	27
ISBN (Electronic)	9783319737829
ISBN (Print)	9783319737812
DOIs	https://doi.org/10.1007/978-3-319-73782-9_1
State	Published - 1 Jan 2018

Keywords

Bone age
Growth hormone
Growth hormone-releasing hormone
Hypopituitarism
Insulin-like growth factor-I
Pituitary
Short stature
Somatotropin release-inhibiting factor (somatostatin)
Transcription factor

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10.1007/978-3-319-73782-9_1

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title = "Childhood Growth Hormone Deficiency and Hypopituitarism",

abstract = "Hypopituitarism is the deficiency in varying degrees of one or multiple pituitary hormones. In this chapter, deficiency of growth hormone (GH) will be discussed, while other hormonal deficiencies are presented elsewhere in this book. To understand GH deficiency (GHD), the mechanisms of GH production and its secretion are first presented. There are multiple etiologies of GHD, and an ever-increasing number of genetic causes have been uncovered. However, the ability to make the diagnosis of GHD still remains difficult, and interpretation of laboratory studies remains controversial.",

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author = "Soto-Rivera, \{Carmen L.\} and Romero, \{Christopher J.\} and Cohen, \{Laurie E.\}",

note = "Publisher Copyright: {\textcopyright} Springer International Publishing AG, part of Springer Nature 2018",

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doi = "10.1007/978-3-319-73782-9\_1",

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T1 - Childhood Growth Hormone Deficiency and Hypopituitarism

AU - Soto-Rivera, Carmen L.

AU - Romero, Christopher J.

AU - Cohen, Laurie E.

N1 - Publisher Copyright: © Springer International Publishing AG, part of Springer Nature 2018

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Hypopituitarism is the deficiency in varying degrees of one or multiple pituitary hormones. In this chapter, deficiency of growth hormone (GH) will be discussed, while other hormonal deficiencies are presented elsewhere in this book. To understand GH deficiency (GHD), the mechanisms of GH production and its secretion are first presented. There are multiple etiologies of GHD, and an ever-increasing number of genetic causes have been uncovered. However, the ability to make the diagnosis of GHD still remains difficult, and interpretation of laboratory studies remains controversial.

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KW - Bone age

KW - Growth hormone

KW - Growth hormone-releasing hormone

KW - Hypopituitarism

KW - Insulin-like growth factor-I

KW - Pituitary

KW - Short stature

KW - Somatotropin release-inhibiting factor (somatostatin)

KW - Transcription factor

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SP - 3

EP - 29

BT - Pediatric Endocrinology

PB - Springer Science+Business Media

ER -

Childhood Growth Hormone Deficiency and Hypopituitarism

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Keywords

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