TY - JOUR
T1 - Childhood, adolescent and adult age at onset and related clinical correlates in obsessive–compulsive disorder
T2 - a report from the International College of Obsessive–Compulsive Spectrum Disorders (ICOCS)
AU - Dell’Osso, Bernardo
AU - Benatti, Beatrice
AU - Hollander, Eric
AU - Fineberg, Naomi
AU - Stein, Dan J.
AU - Lochner, Christine
AU - Nicolini, Humberto
AU - Lanzagorta, Nuria
AU - Palazzo, Carlotta
AU - Altamura, A. Carlo
AU - Marazziti, Donatella
AU - Pallanti, Stefano
AU - Van Ameringen, Michael
AU - Karamustafalioglu, Oguz
AU - Drummond, Lynne M.
AU - Hranov, Luchezar
AU - Figee, Martijn
AU - Grant, Jon E.
AU - Zohar, Joseph
AU - Denys, Damiaan
AU - Menchon, Jose M.
N1 - Publisher Copyright:
© 2016 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2016/10/1
Y1 - 2016/10/1
N2 - Objective: Many studies suggest that age at onset (AAO) is an important factor for clinically differentiating patients with juvenile and adult onset of obsessive–compulsive disorder (OCD). The present international study aimed to assess the prevalence of different AAO groups and compare related socio-demographic and clinical features in a large sample of OCD patients. Methods: A total of 431 OCD outpatients, participating in the ICOCS network, were first categorised in groups with childhood (≤12 years), adolescent (13–17 years) and adult-onset (≥18 years), then in pre-adult and adult onset (≥18 years) and their socio-demographic and clinical features compared. Results: Twenty-one percent (n = 92) of the sample reported childhood onset, 36% (n = 155) adolescent onset, and 43% (n = 184) adult onset. Patients with adult onset showed a significantly higher proportion of females compared with the other subgroups (χ2=10.9, p< 0.05). Childhood- and adolescent-onset patients had been more frequently treated with cognitive behavioural therapy (CBT), compared to adult-onset patients (χ2=11.5; p < 0.05). The pre-adult- versus adult-onset analysis did not show any additional significant difference. Conclusions: The present international multicentre study confirms that OCD onset occurs more frequently before adult age, with approximately one out of five patients showing childhood onset. Pre-adult onset was associated with higher rate of CBT, while adult onset was more prevalent in females.
AB - Objective: Many studies suggest that age at onset (AAO) is an important factor for clinically differentiating patients with juvenile and adult onset of obsessive–compulsive disorder (OCD). The present international study aimed to assess the prevalence of different AAO groups and compare related socio-demographic and clinical features in a large sample of OCD patients. Methods: A total of 431 OCD outpatients, participating in the ICOCS network, were first categorised in groups with childhood (≤12 years), adolescent (13–17 years) and adult-onset (≥18 years), then in pre-adult and adult onset (≥18 years) and their socio-demographic and clinical features compared. Results: Twenty-one percent (n = 92) of the sample reported childhood onset, 36% (n = 155) adolescent onset, and 43% (n = 184) adult onset. Patients with adult onset showed a significantly higher proportion of females compared with the other subgroups (χ2=10.9, p< 0.05). Childhood- and adolescent-onset patients had been more frequently treated with cognitive behavioural therapy (CBT), compared to adult-onset patients (χ2=11.5; p < 0.05). The pre-adult- versus adult-onset analysis did not show any additional significant difference. Conclusions: The present international multicentre study confirms that OCD onset occurs more frequently before adult age, with approximately one out of five patients showing childhood onset. Pre-adult onset was associated with higher rate of CBT, while adult onset was more prevalent in females.
KW - Age at onset
KW - cognitive behavioural therapy
KW - gender
KW - obsessive–compulsive disorder
UR - http://www.scopus.com/inward/record.url?scp=84978755639&partnerID=8YFLogxK
U2 - 10.1080/13651501.2016.1207087
DO - 10.1080/13651501.2016.1207087
M3 - Article
C2 - 27433835
AN - SCOPUS:84978755639
SN - 1365-1501
VL - 20
SP - 210
EP - 217
JO - International Journal of Psychiatry in Clinical Practice
JF - International Journal of Psychiatry in Clinical Practice
IS - 4
ER -