Chemotherapy for hepatocellular carcinoma

Takuji Okusaka, Hideki Ueno, Masafumi Ikeda

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Patients with hepatocellular carcinoma (HCC) frequently show early recurrence even after hepatic resection and local ablation therapy. Moreover, many patients exhibit multiple HCC with or without distant metastasis at the time of initial diagnosis. Accordingly, to improve the overall survival of patients with HCC, effective systemic treatment, including chemotherapy, is needed. No agent has reproducibly documented a high response rate, and few chemotherapeutic regimens show meaningful impact on patient survival. Numerous clinical trials have been conducted to establish effective treatment for patients with HCC.

Original languageEnglish
Pages (from-to)2122-2128
Number of pages7
JournalJapanese Journal of Cancer and Chemotherapy
Issue number13
StatePublished - Dec 2004
Externally publishedYes


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