Chemosensitivity testing with cis-platinum(II) diamminedichloride. II. Preliminary experience in the treatment of carcinoma of the cervix

Gunter Deppe; Carmel J. Cohen; Kaity Yannopoulos; Saul B. Gusberg

doi:10.1016/0090-8258(82)90002-6

Chemosensitivity testing with cis-platinum(II) diamminedichloride. II. Preliminary experience in the treatment of carcinoma of the cervix

Gunter Deppe, Carmel J. Cohen, Kaity Yannopoulos, Saul B. Gusberg

Icahn School of Medicine at Mount Sinai

Research output: Contribution to journal › Article › peer-review

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Abstract

Nineteen previously untreated patients with invasive squamous cell carcinoma of the cervix were given a test dose of cis-platinum(II) diamminedichloride (DDP) prior to treatment with radiotherapy or initial surgery. Two patients who had failed radiation therapy were also tested. Histologic and cytologic characteristics in sequential cervical biopsies and clinical response were employed to determine sensitivity of tumor to platinum and to identify the patient who would most benefit from systemic platinum chemotherapy. No serious side effects were encountered. Standard treatment could be administered without unexpected toxicities or delay.

Original language	English
Pages (from-to)	10-18
Number of pages	9
Journal	Gynecologic Oncology
Volume	13
Issue number	1
DOIs	https://doi.org/10.1016/0090-8258(82)90002-6
State	Published - Feb 1982

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abstract = "Nineteen previously untreated patients with invasive squamous cell carcinoma of the cervix were given a test dose of cis-platinum(II) diamminedichloride (DDP) prior to treatment with radiotherapy or initial surgery. Two patients who had failed radiation therapy were also tested. Histologic and cytologic characteristics in sequential cervical biopsies and clinical response were employed to determine sensitivity of tumor to platinum and to identify the patient who would most benefit from systemic platinum chemotherapy. No serious side effects were encountered. Standard treatment could be administered without unexpected toxicities or delay.",

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Chemosensitivity testing with cis-platinum(II) diamminedichloride. II. Preliminary experience in the treatment of carcinoma of the cervix

Abstract

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