Characterizing female bipolar alcoholic patients presenting for initial evaluation

I. M. Salloum, J. R. Cornelius, J. E. Mezzich, L. Kirisci, D. C. Daley, C. R. Spotts, A. Zuckoff

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


This study examined gender differences of age and race-matched group of bipolar disorder (BPO) patients with comorbid alcohol dependence (AD; n=65; males=35, females=30) to a group of BPO patients without comorbid AD (n=61; males=22, females=39). The two groups were also similar on marital status and frequency of BPO subtypes. The results revealed that female bipolar alcoholic patients were more likely to report depressive symptoms as compared to either male bipolar alcoholics or both male and female non-alcoholic bipolar patients. When compared to male bipolar alcoholics, they had higher frequency of depressed mood, slow motor behavior, low self-esteem, decreased libido, decreased appetite, and higher general anxiety symptoms. On the other hand, female bipolar alcoholics differed from female non-alcoholic bipolar patients on reports of mood lability, depressed mood, low self-esteem, suicidal indicators, decreased libido, and general anxiety symptoms. These results raise the question of whether alcohol increases the frequency of depressive symptoms among female bipolar patients.

Original languageEnglish
Pages (from-to)341-348
Number of pages8
JournalAddictive Behaviors
Issue number3
StatePublished - 2001
Externally publishedYes


  • Alcoholism
  • Bipolar disorder
  • Comorbidity
  • Depression
  • Gender


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