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Characterization of the reversible phosphorylation and activation of ERK8
Iva V. Klevernic
, Margaret J. Stafford
, Nicholas Morrice
, Mark Peggie
, Simon Morton
, Philip Cohen
Research output
:
Contribution to journal
›
Article
›
peer-review
55
Scopus citations
Overview
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Keyphrases
Extracellular Regulated Protein Kinases
100%
Reversible Phosphorylation
100%
Reversible Deactivation
100%
HEK293 Cells
28%
Hydrogen Peroxide
21%
Dephosphorylation
21%
Serine/threonine Phosphatase
21%
ERK2
14%
Insect Cells
14%
Incubation
7%
Growth Factors
7%
Phosphorylation
7%
Autophosphorylation
7%
Protein Phosphatase 2A (PP2A)
7%
Potent Inhibitor
7%
Epidermal Growth Factor
7%
Escherichia Coli
7%
ERK1
7%
Tyrosine Residue
7%
Insulin-like
7%
Okadaic Acid
7%
Relative Rate
7%
Protein Phosphatase Inhibitors
7%
Threonine
7%
Decreased Activity
7%
Protein Tyrosine Phosphatase 1B (PTP1B)
7%
Phosphatase 2A
7%
Myelin Basic Protein
7%
Anisomycin
7%
Osmotic Shock
7%
Phosphatase Inhibitors
7%
Escherichia Coli Cells
7%
Bacteria Cell
7%
Proline-directed Kinase
7%
PPP Family
7%
Immunology and Microbiology
Kinase
100%
Phosphotransferase
100%
phosphorylation
100%
Phosphatase
33%
Threonine
26%
Dephosphorylation
20%
Hydrogen Peroxide
20%
Serine
20%
Escherichia coli
13%
Insect Cell
13%
Tyrosine
13%
In Vitro
13%
Wild Type
6%
Autophosphorylation
6%
Epidermal Growth Factor
6%
Somatomedin C
6%
Myelin
6%
Osmotic Stress
6%
Phosphorylated Protein
6%
Proline
6%
Bacterium
6%
Neuroscience
Protein Kinases
100%
phosphorylation
100%
Threonine
28%
HEK 293 Cells
28%
Hydrogen Peroxide
21%
Serine
21%
Dephosphorylation
21%
In Vitro
14%
Mitogen Activated Protein Kinase 1
14%
Phosphatase Inhibitors
14%
Phosphatase
14%
Epidermal Growth Factor
7%
Mitogen Activated Protein Kinase 3
7%
Okadaic Acid
7%
Insulin-Like Growth Factor 1
7%
Phosphoprotein Phosphatase
7%
Tyrosine
7%
Enzymes
7%
Protein Tyrosine Phosphatase 1B
7%
Myelin Basic Protein
7%
Osmotic Stress
7%
Proline Directed Protein Kinase
7%
Biochemistry, Genetics and Molecular Biology
Protein Kinases
100%
phosphorylation
100%
HEK 293 Cells
26%
Hydrogen Peroxide
20%
Dephosphorylation
20%
Protein Serine/Threonine Phosphatase
20%
Escherichia coli
13%
Enzyme
6%
Phosphoprotein Phosphatase
6%
Wild Type
6%
Insulin-Like Growth Factor 1
6%
Epidermal Growth Factor
6%
Tyrosine
6%
Autophosphorylation
6%
Phosphorylated Protein
6%
Protein Tyrosine Phosphatase
6%
Myelin Basic Protein
6%
Osmotic Stress
6%
Anisomycin
6%
Threonine
6%
Proline
6%
Bacterium
6%
Pharmacology, Toxicology and Pharmaceutical Science
Protein Kinases
100%
Threonine
28%
Hydrogen Peroxide
21%
Serine
21%
Phosphatase
21%
Escherichia coli
14%
Mitogen Activated Protein Kinase 1
14%
Mitogen Activated Protein Kinase 3
7%
Somatomedin C
7%
Epidermal Growth Factor
7%
Phosphoprotein Phosphatase Inhibitor
7%
Tyrosine
7%
Okadaic Acid
7%
2 [1 (3 Amidinothiopropyl) 1h Indol 3 Yl] 3 (1 Methyl 1h Indol 3 Yl)maleimide
7%
Enzymes
7%
Protein Tyrosine Phosphatase 1B
7%
Anisomycin
7%
Myelin Basic Protein
7%
Proline Directed Protein Kinase
7%
Bacterium
7%