Characterization of temperature-sensitive mutants of murine leukemia virus

John R. Stephenson, Stuart A. Aaronson

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


The isolation of temperature-sensitive (ts) mutants of the Rauscher strain of murine leukemia virus (MuLV) is described. These and a number of previously isolated ts mutants of the Kirsten strain of MuLV have been partially characterized and have been separated into three distinct classes based on the stage at which viral replication is blocked at the nonpermissive temperature.

Original languageEnglish
Pages (from-to)53-59
Number of pages7
Issue number1
StatePublished - Jul 1973
Externally publishedYes


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