Changes in plasma prolactin and catecholamine metabolite levels following acute needle stick in children

Richard H. Grayson, Jeffrey M. Halperin, Vanshdeep Sharma, Susan T. Schwartz, Vivian H. Koda, Jeffrey H. Newcorn

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Changes in plasma levels of prolactin (PRL), homovanillic acid (HVA), and 3-methoxy-4-hydroxyphenylglycol (MHPG) following insertion of an indwelling catheter into a forearm vein were assessed in 11 boys with attention-deficit hyperactivity disorder. Results indicated decreases in plasma PRL and HVA, but not MHPG, from the time of needle stick until 105 min post-insertion. These data indicate a significant increase in plasma PRL and HVA in children following needle stick which gradually decreases over a 1.5-2-h period. These stress-induced changes indicate that values obtained immediately after needle insertion cannot be assumed to accurately reflect baseline levels.

Original languageEnglish
Pages (from-to)27-32
Number of pages6
JournalPsychiatry Research
Volume69
Issue number1
DOIs
StatePublished - 3 Mar 1997

Keywords

  • HVA
  • MHPG
  • catecholamines
  • children
  • neurotransmitters
  • prolactin

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