Changed histone acetylation patterns in normal-appearing white matter and early multiple sclerosis lesions

Keyphrases

• Histone Acetylation 100%
• Multiple Sclerosis Lesions 100%
• Normal-appearing White Matter 100%
• Early multiple Sclerosis 100%
• Acetylation Pattern 100%
• Oligodendrocyte Differentiation 60%
• Multiple Sclerosis 40%
• Multiple Sclerosis Treatment 40%
• Disease Duration 40%
• Histone H3 40%
• Acetylation 40%
• Oligodendrocyte 40%
• Histone Acetyltransferase 40%
• Transcription Factor 7-like 2 (TCF7L2) 40%
• Transcription Inhibitors 40%
• Rodents 20%
• Immunoreactivity 20%
• Disease Stage 20%
• White Matter 20%
• Human Brain 20%
• Sex-determining Region Y-box 2 (SOX2) 20%
• Transcriptional Activation 20%
• Older Subjects 20%
• Histone Post-translational Modifications 20%
• Epigenetics 20%
• Nogo-A 20%
• Frontal Lobe 20%
• Acetylated Histone H3 20%
• P300 20%
• Histone Deacetylases 20%
• Acetyl 20%
• Transcript Level 20%
• Chromatin Immunoprecipitation (ChIP) 20%
• Oligodendroglial 20%
• Efficiency Decrease 20%
• Chronic Lesions 20%

Neuroscience

• Multiple Sclerosis 100%
• Histone Acetylation 100%
• Oligodendrocyte 83%
• Histone 66%
• Histone H3 50%
• Histone Acetyltransferase 33%
• Acetylation 33%
• TCF7L2 33%
• Promoter Region 16%
• Frontal Lobe 16%
• Posttranslational Modification 16%
• Transactivation 16%
• Immunoprecipitation 16%
• Histone Deacetylase 16%
• Transcription Initiation 16%
• ID2 16%
• SOX2 16%