Challenges in systematic reviews of economic analyses

Michael Pignone, Somnath Saha, Tom Hoerger, Kathleen N. Lohr, Steven Teutsch, Jeanne Mandelblatt

Research output: Contribution to journalReview articlepeer-review

72 Scopus citations


Economic analyses can provide valuable information for health care decision makers. Systematic reviews of economic analyses can integrate information from multiple studies and provide important insights by systematically examining how differences between models lead to different results. We use our experience in developing and implementing systematic reviews of economic analyses for the U.S. Preventive Services Task Force, particularly our systematic review of the cost-effectiveness of colorectal cancer screening, to illustrate key methodologic challenges and suggest a framework for other researchers in this area.

Original languageEnglish
Pages (from-to)1073-1079
Number of pages7
JournalAnnals of Internal Medicine
Issue number12 II
StatePublished - 21 Jun 2005
Externally publishedYes


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