Cesium-131 permanent seed brachytherapy: Dosimetric evaluation and radiation exposure to surgeons, radiation oncologists, and staff

Bhupesh Parashar, A. Gabriella Wernicke, Al Pavese, Prabhsimranjot Singh, Samuel Trichter, Albert Sabbas, David I. Kutler, William Kuhel, Jeffery L. Port, Paul C. Lee, Dattatreyudu Nori, K. S.Clifford Chao

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Purpose: Cesium-131 ( 131Cs) radioactive seed is Food and Drug Administration approved for permanent seed implant for all cancers, including lung and head and neck (HN) cancers. We describe the first clinical report of 131Cs dosimetry and exposure rates to treating physicians and staff. Methods and Materials: Twenty-eight patients received 131Cs implant for early stage lung and recurrent HN cancers. A nomogram was developed to calculate the number of seeds needed to cover the wedge line with the prescription dose (80Gy). Final dosimetry was obtained after CT planning a few days following the surgical procedure. Radiation exposure to the treating physicians and staff was measured at the completion of the procedure. Results: A nomogram was developed using the variseed software with source data from American Association of Physicists in Medicine TG-43 report. The total volume covered by the prescription isodose line of 131Cs was measured and compared with 125I. The prescription volume was smaller for 131Cs. In addition, the exposure rate with 131Cs was found to be acceptable. Conclusion: Our preliminary experience with 131Cs lung and HN brachytherapy has been very encouraging with excellent dosimetric coverage and acceptable exposure to the treating physicians and staff.

Original languageEnglish
Pages (from-to)508-513
Number of pages6
JournalBrachytherapy
Volume10
Issue number6
DOIs
StatePublished - Nov 2011
Externally publishedYes

Keywords

  • Brachytherapy
  • Cesium-131
  • Head and Neck
  • I
  • Lung
  • Radiation

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