Centrally Mediated Abdominal Pain Syndrome

Stacy S. Tse, Laurie Keefer

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Centrally-mediated abdominal pain syndrome (CAPS) is a disorder of gut-brain dysregulation and is often associated with psychiatric comorbidities. CAPS is not as common as other functional gastrointestinal disorders, but CAPS can exponentially increase healthcare utilization and decrease productivity. CAPS is difficult to diagnose due to a lack of routine objective tests, and relies heavily on a comprehensive medical history. Treatment for CAPS is multipronged, and includes pharmacological approaches as well as psychological methods. A strong relationship between the healthcare provider and patient is essential to successfully managing CAPS.

Original languageEnglish
Title of host publicationEncyclopedia of Gastroenterology, Second Edition
Number of pages8
ISBN (Electronic)9780128124604
StatePublished - 1 Jan 2019


  • Abdominal pain
  • Antidepressants
  • Antiepileptics
  • Atypical antipsychotics
  • Centrally-mediated abdominal pain syndrome
  • Cognitive behavioral therapy
  • Functional gastrointestinal disorders
  • Gut-brain
  • Hypnotherapy
  • Mindfulness
  • Opioids
  • Psychodynamic interpersonal psychotherapy
  • Tricyclic antidepressants


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