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Central Post-Stroke Pain (Thalamic Pain Syndrome)

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

In the early 1900s Dejerine and Roussy first described with pathologic correlation a syndrome of severe unilateral pain following a lesion to the thalamus. Recognition that this syndrome can arise from lesions along the spinothalamic axis led to it being renamed central post-stroke pain (CPSP). Cardinal symptoms of CPSP include temperature and vibration sensitivity and hyperesthesia, dysesthesia, and allodynia. Aside from mild pain relief from amitriptyline, lamotrigine, and gabapentin, no treatment (medicinal or otherwise) has yet been shown to be beneficial in CPSP.

Original languageEnglish
Title of host publicationEssentials of Physical Medicine and Rehabilitation
Subtitle of host publicationMusculoskeletal Disorders, Pain, and Rehabilitation
PublisherElsevier
Pages629-632
Number of pages4
ISBN (Electronic)9780323549479
DOIs
StatePublished - 1 Jan 2018
Externally publishedYes

Keywords

  • Central pain
  • Hyperesthesia
  • Temperature sensitivity
  • Thalamus
  • Vibration sensitivity

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