CDK4/6 and PDGFRA signaling as therapeutic targets in diffuse intrinsic pontine glioma

Keyphrases

• Therapeutic Target 100%
• Cyclin-dependent Kinase 4 (CDK4) 100%
• Platelet-derived Growth Factor Receptor (PDGFR) 100%
• Diffuse Intrinsic Pontine Glioma 100%
• Clinical Trials 33%
• Tumorigenesis 33%
• Pathophysiology 33%
• Novel Therapeutics 33%
• Standard of Care 33%
• Cell of Origin 33%
• Central Nervous System 33%
• Genetic Modification 33%
• Glioma Model 33%
• Specific Difference 33%
• Immunodeficient Mice 33%
• Childhood Brain Tumors 33%
• Additional Therapy 33%
• Autochthonous 33%
• Focal Irradiation 33%
• Modeling Techniques 33%
• Gliomagenesis 33%
• Gene Delivery System 33%
• Mouse Modeling 33%
• System Influences 33%
• Genetic Engineer 33%

Neuroscience

• Central Nervous System 100%
• Carcinogenesis 100%
• Gene Mutation 100%
• Gene Delivery System 100%
• Intracranial Tumor 100%

Medicine and Dentistry

• Disease 100%
• Pontine Glioma 100%
• Clinical Trial 33%
• Carcinogenesis 33%
• Pathophysiology 33%
• Central Nervous System 33%
• Gene Mutation 33%
• Intracranial Tumor 33%
• Gene Delivery 33%