Causal factors for brain tumor and targeted strategies

Priya Ranjan Debata, Gina Marie Curcio, Sumit Mukherjee, Probal Banerjee

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

4 Scopus citations

Abstract

Every five-year plan of each advanced country in the World includes major investments toward medical care. Consequently, vast improvements have taken place, bringing in precise robotic assistance in surgery and spectacular tools for the early detection of a large number of diseases. Advanced genomics and proteomics have ushered in promises for personalized medicine for cancer patients. Yet, the most advanced countries in the World still witness the highest proportion of age adjusted   incidence of brain cancer. Here we submit an overview of the reported etiology, genetics, and epigenetics that appear to be causal to cancers, especially for brain cancers. We discuss in some detail the use and usefulness of simple natural products such as curcumin to minimize the probability of developing cancer and to counteract existing cancers, even those as deadly as primary brain tumors. In this context we address the argument that brain cancers are more of a metabolic rather than a genetic disease and then discuss the acute need for new strategies for cancer therapy. Based on the findings from many laboratories including ours, we end this review advocating strongly for an effort to follow the example of Mother Nature and develop therapeutic strategies involving relatively safe food-derived anticancer agents.

Original languageEnglish
Title of host publicationUniverse of Scales
Subtitle of host publicationFrom Nanotechnology to Cosmology - Symposium in Honor of Minoru M. Freund
EditorsFriedemann Freund, Stephanie Langhoff
PublisherSpringer Science and Business Media, LLC
Pages191-204
Number of pages14
ISBN (Print)9783319022062
DOIs
StatePublished - 2014
Externally publishedYes
EventUniverse of Scales: From Nanotechnology to Cosmology Symposium in Honor of Minoru M. Freund, 2014 - Moffett Field, United States
Duration: 1 Jan 2014 → …

Publication series

NameSpringer Proceedings in Physics
Volume150
ISSN (Print)0930-8989
ISSN (Electronic)1867-4941

Conference

ConferenceUniverse of Scales: From Nanotechnology to Cosmology Symposium in Honor of Minoru M. Freund, 2014
Country/TerritoryUnited States
CityMoffett Field
Period1/01/14 → …

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