Cationic palladium-catalyzed [5 + 2] annulation of 2-acylmethoxyarylboronic acids and allenoates: Synthesis of 1-benzoxepine derivatives

Xufen Yu, Xiyan Lu

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

The 1-benzoxepine derivatives were synthesized conveniently by cationic palladium-catalyzed [5 + 2] annulation reaction of 2-acylmethoxyarylboronic acids with allenoates in high yields. This annulation involves the intramolecular nucleophilic addition to ketones without the formation of π-allylpalladium species.

Original languageEnglish
Pages (from-to)6350-6355
Number of pages6
JournalJournal of Organic Chemistry
Volume76
Issue number15
DOIs
StatePublished - 5 Aug 2011
Externally publishedYes

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