Case of Pediatric Bullous Systemic Lupus Erythematosus Treated with Intravenous Immunoglobulin

Margit Juhász, Megan Rogge, Mary Chen, Annette Czernik, Soo Jung Kim, Lauren Geller

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

This is a case report of a 16-year-old girl recently diagnosed with systemic lupus erythematosus (SLE) who presented with multiple blisters on the face, hands, arms, legs, trunk, and vaginal and oral mucosa. Skin biopsy was consistent with bullous SLE (BSLE). Dapsone is often the first-line treatment option for BSLE, but the patient's history of anemia and leukopenia and long-term immunosuppression requirement for her systemic symptoms raised concerns about dapsone and bone marrow toxicity, especially hemolytic anemia and agranulocytosis. She was started on intravenous immunoglobulin (IVIG), 2 g/kg divided over 3 days, with significant improvement in her cutaneous symptoms. IVIG is a treatment option for BSLE patients in whom agents such as dapsone are contraindicated.

Original languageEnglish
Pages (from-to)e54-e56
JournalPediatric Dermatology
Volume34
Issue number1
DOIs
StatePublished - 1 Jan 2017

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