Cardiovascular Complications of Interatrial Conduction Block: JACC State-of-the-Art Review

David A. Power, Joshua Lampert, Anton Camaj, Solomon W. Bienstock, Nikola Kocovic, Antoni Bayes-Genis, Marc A. Miller, Antoni Bayés-de-Luna, Valentin Fuster

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations


Interatrial block (IAB) is an electrocardiographic pattern describing the conduction delay between the right and left atria. IAB is classified into 3 degrees of block that correspond to decreasing conduction in the region of Bachmann's bundle. Although initially considered benign in nature, specific subsets of IAB have been associated with atrial arrhythmias, elevated thromboembolic stroke risk, cognitive impairment, and mortality. As the pathophysiologic relationships between IAB and stroke are reinforced, investigation has now turned to the potential benefit of early detection, atrial imaging, cardiovascular risk factor modification, antiarrhythmic pharmacotherapy, and stroke prevention with oral anticoagulation. This review provides a contemporary overview of the epidemiology, pathophysiology, diagnosis, and management of IAB, with a focus on future directions.

Original languageEnglish
Pages (from-to)1199-1211
Number of pages13
JournalJournal of the American College of Cardiology
Issue number12
StatePublished - 29 Mar 2022


  • IAB
  • anticoagulation
  • atrial fibrillation
  • interatrial block
  • state-of-the-art review


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