Cardiac transplantation in a patient with protein S deficiency

Talia B. Spanier, Jonathan M. Chen, Donna M. Mancini, Craig R. Smith, Niloo M. Edwards

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Cardiac transplantation was successfully performed in a patient with end-stage ischemic cardiomyopathy and hereditary protein S deficiency who had undergone two previous coronary artery bypass graft procedures. Routine intraoperative heparinization and reversal with protamine was undertaken, and the antifibrinolytic agent aprotinin was infused throughout the procedure without perioperative hemorrhage or thrombosis. Systemic anticoagulation with intravenous heparin was resumed on postoperative day 2, and the patient was then converted to Lovenex as outpatient anticoagulation to facilitate routine surveillance endomyocardial biopsies.

Original languageEnglish
Pages (from-to)1078-1080
Number of pages3
JournalAnnals of Thoracic Surgery
Issue number3
StatePublished - Sep 1999
Externally publishedYes


Dive into the research topics of 'Cardiac transplantation in a patient with protein S deficiency'. Together they form a unique fingerprint.

Cite this