Cardiac regeneration

Raghav Murthy; Aditya Sengupta

doi:10.1016/B978-0-08-102680-9.00006-8

Cardiac regeneration

Raghav Murthy, Aditya Sengupta

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

Abstract

The human heart has been an object of awe and mystery from ancient times. Eight out of every 100 children born have a heart defect. Cardiovascular disease is the leading global cause of death, accounting for more than 17 million deaths per year. For the longest time, the heart has been considered as a postmitotic organ. New evidence has shown that this fabulous organ has some intrinsic regenerative potential. This has led to, in the past couple of decades, extensive investigation into stem cell therapies. This chapter explains the basic theory behind such therapies, the current barriers, the results of current clinical applications, valve regenerative therapies, and pediatric considerations to cardiac regeneration.

Original language	English
Title of host publication	Biointegration of Medical Implant Materials
Publisher	Elsevier
Pages	119-144
Number of pages	26
ISBN (Electronic)	9780081026809
DOIs	https://doi.org/10.1016/B978-0-08-102680-9.00006-8
State	Published - 1 Jan 2019

Keywords

Cardiac regeneration
Cardiomyopathy
Heart failure
Myocardial infarction
Stem cells
Valve regeneration

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10.1016/B978-0-08-102680-9.00006-8

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Cardiac regeneration

Abstract

Keywords

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