Cardiac regeneration

Raghav Murthy, Aditya Sengupta

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


The human heart has been an object of awe and mystery from ancient times. Eight out of every 100 children born have a heart defect. Cardiovascular disease is the leading global cause of death, accounting for more than 17 million deaths per year. For the longest time, the heart has been considered as a postmitotic organ. New evidence has shown that this fabulous organ has some intrinsic regenerative potential. This has led to, in the past couple of decades, extensive investigation into stem cell therapies. This chapter explains the basic theory behind such therapies, the current barriers, the results of current clinical applications, valve regenerative therapies, and pediatric considerations to cardiac regeneration.

Original languageEnglish
Title of host publicationBiointegration of Medical Implant Materials
Number of pages26
ISBN (Electronic)9780081026809
StatePublished - 1 Jan 2019


  • Cardiac regeneration
  • Cardiomyopathy
  • Heart failure
  • Myocardial infarction
  • Stem cells
  • Valve regeneration


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