Cardiac autonomic control is inversely related to blood pressure variability responses to psychological challenge

R. P. Sloan, R. E. Demeersman, P. A. Shapiro, E. Bagiella, J. P. Kuhl, A. S. Zion, M. Paik, M. M. Myers

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

Blood pressure exhibits variability (BPV) at low (0.02- to 0.07-Hz), mid (0.07- to 0.15-Hz)-, and high (0.15- to 0.50-Hz) frequencies. Evidence suggests that BPV responses to challenge are inversely related to cardiac autonomic control. We tested this hypothesis by examining the BPV responses to psychological stressors in 22 normal subjects who differed in cardiac control, operationalized as resting heart period variability (HPV). HPV and BPV were measured noninvasively on a beat-to-beat basis. The stressors produced a significant increase in heart rate and a small but significant increase in diastolic blood pressure. As predicted, the changes in BPV in response to the stressors were inversely related to resting HPV. The results are interpreted in terms of a model of cardiovascular control that holds that BPV originates from feedforward effects of central control of the heart, feedback effects mediated through the baroreflexes, and direct sympathetic vascular effects.

Original languageEnglish
Pages (from-to)H2227-H2232
JournalAmerican Journal of Physiology - Heart and Circulatory Physiology
Volume272
Issue number5 41-5
DOIs
StatePublished - 1997
Externally publishedYes

Keywords

  • heart period variability
  • spectral analysis

Fingerprint

Dive into the research topics of 'Cardiac autonomic control is inversely related to blood pressure variability responses to psychological challenge'. Together they form a unique fingerprint.

Cite this