Cardiac Amyloidosis

Michelle Weisfelner Bloom, Peter D. Gorevic

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Amyloidosis is a pathologic and clinical condition resulting from the accumulation of insoluble aggregates of misfolded proteins in tissues. Extracellular deposition of amyloid fibrils in the myocardium leads to cardiac amyloidosis, which is often overlooked as a cause of diastolic heart failure. Although cardiac amyloidosis was previously believed to have a poor prognosis, recent advances in diagnosis and treatment have emphasized the importance of early recognition and changed management of this condition. This article provides an overview of cardiac amyloidosis and summarizes current screening, diagnosis, evaluation, and treatment options.

Original languageEnglish
Pages (from-to)ITC33-ITC48
JournalAnnals of Internal Medicine
Volume176
Issue number3
DOIs
StatePublished - 1 Mar 2023
Externally publishedYes

Keywords

  • Diagnosis
  • Practice Improvement
  • Screening
  • Treatment

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