Cannabinoids Provoke Alcoholic Steatosis through a Conspiracy of Neighbors

Scott L. Friedman; Natalia Nieto

doi:10.1016/j.cmet.2008.02.002

Cannabinoids Provoke Alcoholic Steatosis through a Conspiracy of Neighbors

Scott L. Friedman
, Natalia Nieto

Research output: Contribution to journal › Short survey › peer-review

5 Scopus citations

Abstract

Cannabinoid signaling by CB₁ receptors drives fibrogenesis and fat accumulation in liver. A report in this issue of Cell Metabolism (Jeong et al., 2008) now links hepatic stellate cells, a resident liver fibrogenic cell type, to the generation of steatosis through production of the endocannabinoid 2-arachidonoylglycerol (2-AG) after ethanol feeding, leading to paracrine stimulation of hepatocyte CB₁ receptors.

Original language	English
Pages (from-to)	187-188
Number of pages	2
Journal	Cell Metabolism
Volume	7
Issue number	3
DOIs	https://doi.org/10.1016/j.cmet.2008.02.002
State	Published - 5 Mar 2008

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10.1016/j.cmet.2008.02.002

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title = "Cannabinoids Provoke Alcoholic Steatosis through a Conspiracy of Neighbors",

abstract = "Cannabinoid signaling by CB1 receptors drives fibrogenesis and fat accumulation in liver. A report in this issue of Cell Metabolism (Jeong et al., 2008) now links hepatic stellate cells, a resident liver fibrogenic cell type, to the generation of steatosis through production of the endocannabinoid 2-arachidonoylglycerol (2-AG) after ethanol feeding, leading to paracrine stimulation of hepatocyte CB1 receptors.",

author = "Friedman, \{Scott L.\} and Natalia Nieto",

year = "2008",

month = mar,

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doi = "10.1016/j.cmet.2008.02.002",

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journal = "Cell Metabolism",

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T1 - Cannabinoids Provoke Alcoholic Steatosis through a Conspiracy of Neighbors

AU - Friedman, Scott L.

AU - Nieto, Natalia

PY - 2008/3/5

Y1 - 2008/3/5

N2 - Cannabinoid signaling by CB1 receptors drives fibrogenesis and fat accumulation in liver. A report in this issue of Cell Metabolism (Jeong et al., 2008) now links hepatic stellate cells, a resident liver fibrogenic cell type, to the generation of steatosis through production of the endocannabinoid 2-arachidonoylglycerol (2-AG) after ethanol feeding, leading to paracrine stimulation of hepatocyte CB1 receptors.

AB - Cannabinoid signaling by CB1 receptors drives fibrogenesis and fat accumulation in liver. A report in this issue of Cell Metabolism (Jeong et al., 2008) now links hepatic stellate cells, a resident liver fibrogenic cell type, to the generation of steatosis through production of the endocannabinoid 2-arachidonoylglycerol (2-AG) after ethanol feeding, leading to paracrine stimulation of hepatocyte CB1 receptors.

UR - https://www.scopus.com/pages/publications/39649090030

U2 - 10.1016/j.cmet.2008.02.002

DO - 10.1016/j.cmet.2008.02.002

M3 - Short survey

C2 - 18316020

AN - SCOPUS:39649090030

SN - 1550-4131

VL - 7

SP - 187

EP - 188

JO - Cell Metabolism

JF - Cell Metabolism

IS - 3

ER -

Cannabinoids Provoke Alcoholic Steatosis through a Conspiracy of Neighbors

Abstract

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