Cannabinoids Provoke Alcoholic Steatosis through a Conspiracy of Neighbors

Scott L. Friedman; Natalia Nieto

doi:10.1016/j.cmet.2008.02.002

Cannabinoids Provoke Alcoholic Steatosis through a Conspiracy of Neighbors

Scott L. Friedman, Natalia Nieto

Research output: Contribution to journal › Short survey › peer-review

1 Scopus citations

Abstract

Cannabinoid signaling by CB₁ receptors drives fibrogenesis and fat accumulation in liver. A report in this issue of Cell Metabolism (Jeong et al., 2008) now links hepatic stellate cells, a resident liver fibrogenic cell type, to the generation of steatosis through production of the endocannabinoid 2-arachidonoylglycerol (2-AG) after ethanol feeding, leading to paracrine stimulation of hepatocyte CB₁ receptors.

Original language	English
Pages (from-to)	187-188
Number of pages	2
Journal	Cell Metabolism
Volume	7
Issue number	3
DOIs	https://doi.org/10.1016/j.cmet.2008.02.002
State	Published - 5 Mar 2008

Access to Document

10.1016/j.cmet.2008.02.002

Cite this

@article{e5d1aa2e4b834a27bc263e0136af5374,

title = "Cannabinoids Provoke Alcoholic Steatosis through a Conspiracy of Neighbors",

abstract = "Cannabinoid signaling by CB1 receptors drives fibrogenesis and fat accumulation in liver. A report in this issue of Cell Metabolism (Jeong et al., 2008) now links hepatic stellate cells, a resident liver fibrogenic cell type, to the generation of steatosis through production of the endocannabinoid 2-arachidonoylglycerol (2-AG) after ethanol feeding, leading to paracrine stimulation of hepatocyte CB1 receptors.",

author = "Friedman, {Scott L.} and Natalia Nieto",

year = "2008",

month = mar,

day = "5",

doi = "10.1016/j.cmet.2008.02.002",

language = "English",

volume = "7",

pages = "187--188",

journal = "Cell Metabolism",

issn = "1550-4131",

publisher = "Cell Press",

number = "3",

}

TY - JOUR

T1 - Cannabinoids Provoke Alcoholic Steatosis through a Conspiracy of Neighbors

AU - Friedman, Scott L.

AU - Nieto, Natalia

PY - 2008/3/5

Y1 - 2008/3/5

N2 - Cannabinoid signaling by CB1 receptors drives fibrogenesis and fat accumulation in liver. A report in this issue of Cell Metabolism (Jeong et al., 2008) now links hepatic stellate cells, a resident liver fibrogenic cell type, to the generation of steatosis through production of the endocannabinoid 2-arachidonoylglycerol (2-AG) after ethanol feeding, leading to paracrine stimulation of hepatocyte CB1 receptors.

AB - Cannabinoid signaling by CB1 receptors drives fibrogenesis and fat accumulation in liver. A report in this issue of Cell Metabolism (Jeong et al., 2008) now links hepatic stellate cells, a resident liver fibrogenic cell type, to the generation of steatosis through production of the endocannabinoid 2-arachidonoylglycerol (2-AG) after ethanol feeding, leading to paracrine stimulation of hepatocyte CB1 receptors.

UR - http://www.scopus.com/inward/record.url?scp=39649090030&partnerID=8YFLogxK

U2 - 10.1016/j.cmet.2008.02.002

DO - 10.1016/j.cmet.2008.02.002

M3 - Short survey

C2 - 18316020

AN - SCOPUS:39649090030

SN - 1550-4131

VL - 7

SP - 187

EP - 188

JO - Cell Metabolism

JF - Cell Metabolism

IS - 3

ER -

Cannabinoids Provoke Alcoholic Steatosis through a Conspiracy of Neighbors

Abstract

Access to Document

Fingerprint

Cite this