Cancer screening in patients infected with HIV

Keith Sigel, Robert Dubrow, Michael Silverberg, Kristina Crothers, Scott Braithwaite, Amy Justice

Research output: Contribution to journalArticlepeer-review

64 Scopus citations


Non-AIDS-defining cancers are a rising health concern among HIV-infected patients. Cancer screening isnow an important component of health maintenance in HIVclinical practice. The decision to screen an HIV-infectedpatient for cancer should include an assessment of individualizedrisk for the particular cancer, life expectancy, and theharms and benefits associated with the screening test and itspotential outcome. HIV-infected patients are at enhanced riskof several cancers compared to the general population; analcancer, hepatocellular carcinoma, Hodgkin's lymphoma, andlung cancer all have good evidence demonstrating anenhanced risk in HIV-infected persons. A number of cancerscreening interventions have shown benefit for specificcancers in the general population, but data on the application

Original languageEnglish
Pages (from-to)142-152
Number of pages11
JournalCurrent HIV/AIDS Reports
Issue number3
StatePublished - Sep 2011


  • Alpha-fetoprotein (AFP)
  • Anal cancer
  • Anal cytology
  • Breast cancer
  • Cancer screening
  • Cervical cancer
  • Colonoscopy
  • Colorectal cancer
  • Combination antiretroviral therapy(cART)
  • Digital rectal examination (DRE)
  • Fecal occult blood testing (FOBT)
  • Hepatocellular cancer
  • High-resolution anoscopy (HRA)
  • Human immunodeficiency virus (HIV)
  • Life-expectancy
  • Low-dose CT
  • Lung cancer
  • Mammography
  • Non-AIDS defining cancers (NADCs)
  • Pap testing
  • Payoff time
  • Prostate cancer
  • Sigmoidoscopy
  • Ultrasonography


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