TY - JOUR
T1 - Cancer prevention in patients with inflammatory bowel disease
AU - Itzkowitz, Steven H.
N1 - Funding Information:
Supported by the National Cancer Institute (RO1 CA81363), the Burrill B. Crohn Research Foundation, and The Chemotherapy Foundation.
PY - 2002/12
Y1 - 2002/12
N2 - Colorectal cancer is an important, and often dreaded, consequence of long-standing UC and Crohn's colitis. Surveillance colonoscopy, despite its limitations, is beneficial for detecting earlier stage cancers and, probably, mortality reduction. Agents such as anti-inflammatory medications, folic acid, and ursodeoxycholic acid show promise for chemoprevention in this disease. Future research will help to define better the natural history of dysplasia in IBD, and to determine how molecular approaches may be integrated into surveillance programs to reduce CRC risk.
AB - Colorectal cancer is an important, and often dreaded, consequence of long-standing UC and Crohn's colitis. Surveillance colonoscopy, despite its limitations, is beneficial for detecting earlier stage cancers and, probably, mortality reduction. Agents such as anti-inflammatory medications, folic acid, and ursodeoxycholic acid show promise for chemoprevention in this disease. Future research will help to define better the natural history of dysplasia in IBD, and to determine how molecular approaches may be integrated into surveillance programs to reduce CRC risk.
UR - https://www.scopus.com/pages/publications/0036895605
U2 - 10.1016/S0889-8553(02)00047-X
DO - 10.1016/S0889-8553(02)00047-X
M3 - Review article
C2 - 12489282
AN - SCOPUS:0036895605
SN - 0889-8553
VL - 31
SP - 1133
EP - 1144
JO - Gastroenterology Clinics of North America
JF - Gastroenterology Clinics of North America
IS - 4
ER -