Abstract

Type 1 conventional dendritic cells (cDC1s) are critical for CD8+ T cell-mediated tumor control. In this issue of Immunity, Bayerl et al.1 expose a mechanism leading to cancer progression where prostaglandin E2 induces dysfunctional cDC1s, which cannot coordinate CD8+ T cell migration and expansion.

Original languageEnglish
Pages (from-to)1165-1167
Number of pages3
JournalImmunity
Volume56
Issue number6
DOIs
StatePublished - 13 Jun 2023

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