Abstract
Type 1 conventional dendritic cells (cDC1s) are critical for CD8+ T cell-mediated tumor control. In this issue of Immunity, Bayerl et al.1 expose a mechanism leading to cancer progression where prostaglandin E2 induces dysfunctional cDC1s, which cannot coordinate CD8+ T cell migration and expansion.
Original language | English |
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Pages (from-to) | 1165-1167 |
Number of pages | 3 |
Journal | Immunity |
Volume | 56 |
Issue number | 6 |
DOIs |
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State | Published - 13 Jun 2023 |