Cancer-directed surgery in malignant pleural mesothelioma: extrapleural pneumonectomy and pleurectomy/decortication

Brian Housman, Andrea S. Wolf

Research output: Contribution to journalReview articlepeer-review

Abstract

Malignant pleural mesothelioma (MPM) is a primary solid malignancy related to inhalational asbestos exposure. Despite advances in therapy, MPM remains challenging to treat with a post-treatment survival of only 15% at 5- year. In recent years, extra-pleural pneumonectomy has decreased in popularity due to a high morbidity rate and mortality compared to pleurectomy/decortication and other therapeutic alternatives. In this review, we will discuss both procedures, outcomes, ongoing studies, and the roles of surgery in the future treatment of this disease.

Original languageEnglish
Article number4377
JournalJournal of Cancer Metastasis and Treatment
Volume7
DOIs
StatePublished - 2021

Keywords

  • Surgery for malignant pleural mesothelioma
  • extrapleural pneumonectomy
  • pleurectomy/decortication
  • recurrence perioperative mortality

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