Can we talk? The cryptic communications of hepatic stellate cells in lipid metabolism

Scott L. Friedman

doi:10.1016/j.cmet.2025.03.008

Can we talk? The cryptic communications of hepatic stellate cells in lipid metabolism

Scott L. Friedman

Research output: Contribution to journal › Comment/debate

2 Scopus citations

Abstract

The contributions of signals generated by hepatic stellate cells that regulate hepatocyte lipid and glucose homeostasis are largely unexplored. The article by Hansen et al. introduces a novel role of plasmalemma vesicle-associated protein (PLVAP), a membrane protein expressed by hepatic stellate cells, in regulating these pathways in hepatocytes during fasting.

Original language	English
Pages (from-to)	794-796
Number of pages	3
Journal	Cell Metabolism
Volume	37
Issue number	4
DOIs	https://doi.org/10.1016/j.cmet.2025.03.008
State	Published - 1 Apr 2025

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title = "Can we talk? The cryptic communications of hepatic stellate cells in lipid metabolism",

abstract = "The contributions of signals generated by hepatic stellate cells that regulate hepatocyte lipid and glucose homeostasis are largely unexplored. The article by Hansen et al. introduces a novel role of plasmalemma vesicle-associated protein (PLVAP), a membrane protein expressed by hepatic stellate cells, in regulating these pathways in hepatocytes during fasting.",

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N2 - The contributions of signals generated by hepatic stellate cells that regulate hepatocyte lipid and glucose homeostasis are largely unexplored. The article by Hansen et al. introduces a novel role of plasmalemma vesicle-associated protein (PLVAP), a membrane protein expressed by hepatic stellate cells, in regulating these pathways in hepatocytes during fasting.

AB - The contributions of signals generated by hepatic stellate cells that regulate hepatocyte lipid and glucose homeostasis are largely unexplored. The article by Hansen et al. introduces a novel role of plasmalemma vesicle-associated protein (PLVAP), a membrane protein expressed by hepatic stellate cells, in regulating these pathways in hepatocytes during fasting.

UR - https://www.scopus.com/pages/publications/105000937303

U2 - 10.1016/j.cmet.2025.03.008

DO - 10.1016/j.cmet.2025.03.008

M3 - Comment/debate

AN - SCOPUS:105000937303

SN - 1550-4131

VL - 37

SP - 794

EP - 796

JO - Cell Metabolism

JF - Cell Metabolism

IS - 4

ER -

Can we talk? The cryptic communications of hepatic stellate cells in lipid metabolism

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