CABG vs. PCI for left main revascularization

Coronary artery disease affecting the left main coronary artery is a serious medical condition due to the large myocardial territory at risk. Although coronary artery bypass grafting was considered the gold standard for left main disease in the past, percutaneous coronary intervention has recently emerged as a viable alternative in multiple clinical scenarios. Despite that, the optimal treatment approach for left main coronary artery disease patients with specific preexisting comorbid conditions, procedural characteristics, and clinical parameters remains unclear. The growing body of evidence from real-world registries as well as randomized clinical trials may help guide clinical decision-making. The role of a multidisciplinary Heart Team in tailoring the treatment strategy based on individualized risk assessment is of utmost significance to improve outcomes in these high-risk patients.