Bupropion for Blau syndrome

Eric Lewin Altschuler, Richard E. Kast

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Blau syndrome (BS) is an autosomal dominantly inherited disease characterized by granulomas and arthritis. The gene mutated in BS was recently found to be CARD15. Mutations in this gene also occur in about 20% of patients with Crohn's disease (CD), though with different mutations than in the Crohn's patients. We are not aware of any cure or specific treatment for BS. We have found that bupropion is effective for CD, and we now suggest that bupropion be considered for treatment of BS.

Original languageEnglish
Pages (from-to)297-298
Number of pages2
JournalMedical Hypotheses
Issue number2
StatePublished - 2004


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