TY - JOUR
T1 - Bridging the knowledge gap
T2 - From microbiome composition to function
AU - Faith, Jeremiah J.
N1 - Publisher Copyright:
© 2015 The Author. Published under the terms of the CC BY 4.0 license.
PY - 2015/3/1
Y1 - 2015/3/1
N2 - Despite the wealth of metagenomic sequencing data, the functions of most bacterial genes from the mammalian microbiota have remained poorly understood. In their recent study (Yaung et al 2015), Wang, Gerber, and colleagues present a platform which allows functional mining of bacterial genomes for genes that contribute to fitness in vivo and holds great potential for forward engineering microbes with enhanced colonization abilities in the microbiota. A functional metagenomics platform presented by Wang, Gerber, and colleagues (Yaung et al 2015) allows mining of bacterial genomes for genes that contribute to fitness in vivo and holds great potential for forward engineering microbes with enhanced colonization abilities in the microbiota.
AB - Despite the wealth of metagenomic sequencing data, the functions of most bacterial genes from the mammalian microbiota have remained poorly understood. In their recent study (Yaung et al 2015), Wang, Gerber, and colleagues present a platform which allows functional mining of bacterial genomes for genes that contribute to fitness in vivo and holds great potential for forward engineering microbes with enhanced colonization abilities in the microbiota. A functional metagenomics platform presented by Wang, Gerber, and colleagues (Yaung et al 2015) allows mining of bacterial genomes for genes that contribute to fitness in vivo and holds great potential for forward engineering microbes with enhanced colonization abilities in the microbiota.
UR - http://www.scopus.com/inward/record.url?scp=84925855536&partnerID=8YFLogxK
U2 - 10.15252/msb.20156045
DO - 10.15252/msb.20156045
M3 - Short survey
C2 - 26148349
AN - SCOPUS:84925855536
SN - 1744-4292
VL - 11
JO - Molecular Systems Biology
JF - Molecular Systems Biology
IS - 3
M1 - 793
ER -