Bradykinin for the treatment of cardiovascular disease

S. A. Palkhiwala, W. H. Frishman, S. Warshafsky

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

Bradykinin is a vasoactive kinin known to be involved in many biologic processes. Levels of bradykinin have been shown to be elevated in a number of cardiac diseases. It is thought that these elevated levels play a protective role in cardiovascular diseases. Preliminary studies have demonstrated that bradykinin may have beneficial effects on a wide spectrum of cardiovascular disorders. Though much study is still required, bradykinin augmentation represents an exciting new target for the treatment of cardiovascular disease.

Original languageEnglish
Pages (from-to)333-339
Number of pages7
JournalHeart Disease
Volume3
Issue number5
DOIs
StatePublished - 2001
Externally publishedYes

Keywords

  • Bradykinin
  • Cardiovascular disease
  • Heart failure
  • Hypertension
  • Hypertrophy
  • Ischemia
  • Kinin
  • Receptor agonist
  • Vascular remodeling

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